Anyone ever tried it before? How did it go? Any stories to share, tales of glory or heartbreak?
For everyone who doesn't have a clue as to what I'm talking about, it's a pokémon user induced set of rules that can be applied to any pokémon game. The two main one are these: You may only capture the first pokémon you encounter in each area, and, if a pokémon faints it is considered "dead" and must be released into the wild. There are a number of other variant rules to make it easier or harder accordingly.
Nuzlocke Comics for more info and background.