He should be, lol. Cade is an original vampire. He's existed since pretty much the beginning of time. He was a part of the original vampire family. Which technically means, his family created Bell and Regan at one point or another. He should definitely be afraid of Cade, though that doesn't mean he can't stand up to him. Just keep in mind that Cade comes from lifetimes of simply killing others who so much as cough in his direction. So if Regan is going to stand up to him, he'd better have a darn good reason, so that Cade will have a 'respect' for him for doing it, and not a reason to kill him or throw him in a dungeon, too.
As far as really getting Regan twisted into the story somehow. I don't know. *sigh* Maybe we can give it a little while and see what else unfolds before we start making too many plans. I think it's the plans that tend to kill role-plays. It's waiting for the opportune moment to spring something that really makes it enjoyable for everyone. So far our twists have been Red dying, Gwen turning vampire, and Katerina in the dungeon/Cade's bad habit. Nate hasn't really had a twist yet either. Perhaps it can be something involving him? I'm not sure how though. Like I said, it's hard to plan. Perhaps we should wait and see a fitting time to throw another curveball into the mix.
I feel like having Regan somehow related to maybe Cade's one true love, or something along the lines of a past connection to one of them would be coolest.