Vaguely. I never got the chance to get my hands on a good copy of the book, so I'm vague on the details. I've seen the movie, but I doubt that helps much.
Cardea is an elder of the Clan Brujah who was Embraced during the Elizabethan period. She's a very masculine woman who typically dresses and acts like a man. She doesn't cross-dress in the sense of passing as a man but rather takes the masculine role. Therefore she's definitely not the damsel type.
In this story it's been a very long time since she's been in a relationship (not since before she was Embraced) and it's the first time she's fallen in love with a woman - let alone a mortal woman.