Head wise I have two issues I guess.
Anosmia - no sense of smell
Barometric headaches - Upside: it predicts changes in weather. Downside: They can be so bad some days I can't see and can't get out of bed.

Anosmia is a bit of an annoying 'disability'. I get food poisoning sometimes since I can't smell when certain foods are expired. After years of being with me, family and friends still ask me to 'smell this, it's amazing!' only for me to glare at them in response since they keep forgetting. I also live in a house with a gas cooker so it's potentially deadly for me if there's a gas leak.

They say that smell is strongly associated with memories. I barely have emotions linked to memories granted I can remember things at all.